valosin-containing protein (VCP)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:CDC48 gptkb:p97
gptkbp:associatedWith	gptkb:amyotrophic_lateral_sclerosis_(ALS) gptkb:multisystem_proteinopathy gptkb:inclusion_body_myopathy_with_Paget_disease_of_bone_and_frontotemporal_dementia_(IBMPFD)
gptkbp:biologicalProcess	ATP binding protein binding ubiquitin binding
gptkbp:cellularComponent	gptkb:endoplasmic_reticulum gptkb:nucleus gptkb:cytoplasm
gptkbp:discoveredIn	1994
gptkbp:encodedBy	gptkb:VCP_gene
gptkbp:essentialGene	yes
gptkbp:family	gptkb:AAA_ATPase_family
gptkbp:function	gptkb:endoplasmic_reticulum-associated_degradation_(ERAD) cell cycle regulation protein degradation autophagy ubiquitin-dependent protein catabolic process ATPase activity
https://www.w3.org/2000/01/rdf-schema#label	valosin-containing protein (VCP)
gptkbp:interactsWith	gptkb:PLAA gptkb:UBXN2A gptkb:VIMP gptkb:UBXD1 gptkb:Derlin-1 gptkb:NPL4 gptkb:UFD1L gptkb:atlastin-1 gptkb:UBXN1 p47
gptkbp:locatedOnChromosome	gptkb:chromosome_9p13.3
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:orthologIn	gptkb:Mus_musculus gptkb:Saccharomyces_cerevisiae gptkb:Drosophila_melanogaster
gptkbp:PDB	gptkb:5FTK gptkb:3CF3 5C1B
gptkbp:postTranslationalModification	phosphorylation sumoylation ubiquitination
gptkbp:reviewedBy	gptkb:GeneCards gptkb:OMIM gptkb:UniProt
gptkbp:structure	hexamer
gptkbp:UniProtID	gptkb:P55072
gptkbp:bfsParent	gptkb:UBX_domain-containing_protein_1
gptkbp:bfsLayer	7