|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:VCP
gptkb:valosin-containing_protein
|
|
gptkbp:associatedWith
|
gptkb:amyotrophic_lateral_sclerosis_(ALS)
gptkb:multisystem_proteinopathy
gptkb:inclusion_body_myopathy_with_Paget_disease_of_bone_and_frontotemporal_dementia_(IBMPFD)
|
|
gptkbp:biologicalProcess
|
ATP binding
protein binding
|
|
gptkbp:cellularComponent
|
gptkb:endoplasmic_reticulum
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:discoveredBy
|
gptkb:Koller_and_Brownstein
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:Entrez_Gene_ID
|
7415
|
|
gptkbp:enzymeClassification
|
gptkb:EC_3.6.4.6
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:function
|
protein degradation
ubiquitin-dependent protein catabolic process
ATPase activity
|
|
gptkbp:gene
|
gptkb:VCP_gene
|
|
gptkbp:HGNC_ID
|
12666
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
p97
|
|
gptkbp:interactsWith
|
gptkb:PLAA
gptkb:NPL4
gptkb:SVIP
gptkb:UFD1L
gptkb:atlastin-1
p47
|
|
gptkbp:involvedIn
|
gptkb:endoplasmic_reticulum-associated_degradation_(ERAD)
DNA repair
cell cycle regulation
autophagy
|
|
gptkbp:length
|
806 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_9p13.3
|
|
gptkbp:molecularWeight
|
~89 kDa
|
|
gptkbp:OMIM
|
601023
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
gptkb:Saccharomyces_cerevisiae_(Cdc48)
|
|
gptkbp:PDB
|
gptkb:3CF1
gptkb:5FTK
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:requires
|
cell viability
|
|
gptkbp:structure
|
hexamer
|
|
gptkbp:targetOfDrug
|
CB-5083
NMS-873
|
|
gptkbp:UniProtID
|
gptkb:P55072
|
|
gptkbp:bfsParent
|
gptkb:VCP
gptkb:ATPases_Associated_with_diverse_cellular_Activities
|
|
gptkbp:bfsLayer
|
7
|