AAA ATPase family

GPTKB entity

Statements (43)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:characteristic conserved ATPase domain
ATP-dependent activity
energy-dependent conformational changes
hexameric ring structure
mechanochemical enzyme
gptkbp:conservedIn gptkb:Walker_A_motif
gptkb:Walker_B_motif
gptkb:arginine_finger
gptkbp:domain gptkb:AAA_domain
gptkbp:enzymeClassification EC 3.6.4.-
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:function protein unfolding
protein disaggregation
ATP hydrolysis
molecular chaperone activity
gptkbp:GO_term GO:0005524
GO:0042623
gptkbp:hasMember gptkb:NSF
gptkb:ClpA
gptkb:ClpB
gptkb:ClpX
gptkb:Hsp104
gptkb:VCP/p97
Pex1
Pex6
gptkbp:hasPfamID gptkb:PF00004
https://www.w3.org/2000/01/rdf-schema#label AAA ATPase family
gptkbp:InterPro gptkb:IPR003593
gptkbp:involvedIn cell cycle regulation
vesicle trafficking
DNA replication
protein degradation
protein quality control
membrane fusion
organelle biogenesis
chromatin remodeling
peroxisome biogenesis
gptkbp:partOf gptkb:P-loop_NTPase_superfamily
gptkbp:bfsParent gptkb:SPG4_gene
gptkbp:bfsLayer 7