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gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:characteristic
|
conserved ATPase domain
ATP-dependent activity
energy-dependent conformational changes
hexameric ring structure
mechanochemical enzyme
|
|
gptkbp:conservedIn
|
gptkb:Walker_A_motif
gptkb:Walker_B_motif
gptkb:arginine_finger
|
|
gptkbp:domain
|
gptkb:AAA_domain
|
|
gptkbp:enzymeClassification
|
EC 3.6.4.-
|
|
gptkbp:foundIn
|
gptkb:Bacteria
archaea
eukaryotes
|
|
gptkbp:function
|
protein unfolding
protein disaggregation
ATP hydrolysis
molecular chaperone activity
|
|
gptkbp:GO_term
|
GO:0005524
GO:0042623
|
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gptkbp:hasMember
|
gptkb:NSF
gptkb:ClpA
gptkb:ClpB
gptkb:ClpX
gptkb:Hsp104
gptkb:VCP/p97
Pex1
Pex6
|
|
gptkbp:hasPfamID
|
gptkb:PF00004
|
|
gptkbp:InterPro
|
gptkb:IPR003593
|
|
gptkbp:involvedIn
|
cell cycle regulation
vesicle trafficking
DNA replication
protein degradation
protein quality control
membrane fusion
organelle biogenesis
chromatin remodeling
peroxisome biogenesis
|
|
gptkbp:partOf
|
gptkb:P-loop_NTPase_superfamily
|
|
gptkbp:bfsParent
|
gptkb:valosin-containing_protein_(VCP)
gptkb:ATPases_Associated_with_diverse_cellular_Activities_protein_family
gptkb:NMS-873_(inhibitor)
gptkb:VCP_gene
gptkb:valosin-containing_protein
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AAA ATPase family
|