VCP gene

URI: https://gptkb.org/entity/VCP_gene

GPTKB entity

Statements (99)

Predicate	Object
gptkbp:instanceOf	gptkb:gene
gptkbp:alias	gptkb:CDC48 gptkb:TERA IBMPFD
gptkbp:associatedWith	gptkb:multisystem_proteinopathy amyotrophic lateral sclerosis inclusion body myopathy with early-onset Paget disease and frontotemporal dementia
gptkbp:chromosomeArm	p
gptkbp:discoveredBy	Koller et al.
gptkbp:discoveredIn	1992
gptkbp:encodes	valosin containing protein
gptkbp:Entrez_Gene_ID	7415 ENSG00000165280
gptkbp:expressedIn	ubiquitous
gptkbp:fullName	valosin containing protein
gptkbp:function	gptkb:endoplasmic_reticulum-associated_degradation_(ERAD) cell cycle regulation protein degradation autophagy ubiquitin-dependent protein catabolic process
gptkbp:HGNC_ID	12666
https://www.w3.org/2000/01/rdf-schema#label	VCP gene
gptkbp:interactsWith	gptkb:ATXN3 gptkb:NSFL1C gptkb:PLAA gptkb:SPATA2 gptkb:UBXN10 gptkb:UBXN11 gptkb:UBXN12 gptkb:UBXN13 gptkb:UBXN14 gptkb:UBXN15 gptkb:UBXN16 gptkb:UBXN17 gptkb:UBXN18 gptkb:UBXN19 gptkb:UBXN20 gptkb:UBXN21 gptkb:UBXN22 gptkb:UBXN23 gptkb:UBXN24 gptkb:UBXN25 gptkb:UBXN26 gptkb:UBXN27 gptkb:UBXN28 gptkb:UBXN29 gptkb:UBXN2A gptkb:UBXN2B gptkb:UBXN30 gptkb:UBXN31 gptkb:UBXN32 gptkb:UBXN33 gptkb:UBXN34 gptkb:UBXN35 gptkb:UBXN36 gptkb:UBXN37 gptkb:UBXN38 gptkb:UBXN39 gptkb:UBXN3B gptkb:UBXN4 gptkb:UBXN40 gptkb:UBXN41 gptkb:UBXN42 gptkb:UBXN43 gptkb:UBXN44 gptkb:UBXN45 gptkb:UBXN46 gptkb:UBXN47 gptkb:UBXN48 gptkb:UBXN49 gptkb:UBXN5 gptkb:UBXN50 gptkb:UBXN6 gptkb:UBXN8 gptkb:UBXN9 gptkb:FAF1 gptkb:UBXN7 gptkb:YOD1 gptkb:Derlin-1 gptkb:NPL4 gptkb:UFD1L gptkb:UBXN1 p47
gptkbp:length	17 exons
gptkbp:locatedOnChromosome	9 9p13.3
gptkbp:mutationAssociatedWith	causes Paget disease of bone causes frontotemporal dementia causes inclusion body myopathy causes multisystem proteinopathy
gptkbp:OMIM	601023
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:orthologInMouse	Vcp
gptkbp:orthologInYeast	gptkb:CDC48
gptkbp:proteinFamily	gptkb:AAA_ATPase_family
gptkbp:UniProtID	gptkb:P55072
gptkbp:bfsParent	gptkb:VCP gptkb:p97/VCP
gptkbp:bfsLayer	7