transient receptor potential cation channel subfamily V member 1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein ion channel
gptkbp:abbreviation	TRPV1
gptkbp:activatedBy	gptkb:protons gptkb:capsaicin gptkb:anandamide heat
gptkbp:associatedWith	peripheral neuropathy nociception inflammatory pain hyperalgesia
gptkbp:discoveredBy	gptkb:David_Julius
gptkbp:discoveredIn	1997
gptkbp:encodedBy	gptkb:TRPV1_gene
gptkbp:enemyOf	gptkb:capsaicin gptkb:anandamide gptkb:capsazepine gptkb:resiniferatoxin AMG 517
gptkbp:Entrez_Gene_ID	7442
gptkbp:expressedIn	gptkb:skin gptkb:urinary_bladder gptkb:dorsal_root_ganglion brain sensory neurons
gptkbp:family	gptkb:TRP_channel_family
gptkbp:foundIn	gptkb:human gptkb:mouse right
gptkbp:function	non-selective cation channel
gptkbp:HGNC_ID	HGNC:17982
https://www.w3.org/2000/01/rdf-schema#label	transient receptor potential cation channel subfamily V member 1
gptkbp:length	839 amino acids
gptkbp:locatedOnChromosome	chromosome 17p13
gptkbp:location	gptkb:plasma_membrane
gptkbp:molecularWeight	95 kDa
gptkbp:OMIM	602076
gptkbp:PDB	3J5P
gptkbp:permeableTo	Mg2+ Ca2+ Na+
gptkbp:role	inflammation pain perception thermosensation
gptkbp:structure	tetramer
gptkbp:subfamily	TRPV
gptkbp:transmembraneDomains	6
gptkbp:UniProtID	gptkb:Q8NER1
gptkbp:bfsParent	gptkb:TRPV1_receptor
gptkbp:bfsLayer	6