Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
phytotoxin |
| gptkbp:CASNumber |
124608-87-1
|
| gptkbp:chemicalFormula |
C37H40O9
|
| gptkbp:discoveredBy |
John W. Daly
|
| gptkbp:discoveredIn |
1975
|
| gptkbp:foundIn |
Euphorbia poissonii
Euphorbia resinifera |
| gptkbp:hasSMILES |
COC(=O)/C=C/C(C)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C
|
| https://www.w3.org/2000/01/rdf-schema#label |
resiniferatoxin
|
| gptkbp:IUPACName |
(4aR,5S,6R,8aR,9R,10S,12S,13aR,13bR)-6,9,13a,13b-tetramethyl-4,10,12-trioxo-2,3,4,4a,5,6,7,8,8a,9,10,11,12,13,13a,13b-hexadecahydro-1H-cyclopenta[a]phenanthren-5-yl (E)-4-methoxy-3-methylbut-2-enoate
|
| gptkbp:mechanismOfAction |
TRPV1 agonist
|
| gptkbp:meltingPoint |
238–240 °C
|
| gptkbp:MeSH_ID |
D054856
|
| gptkbp:molecularWeight |
628.71 g/mol
|
| gptkbp:PubChem_CID |
6441027
CHEBI:8881 CHEMBL375354 |
| gptkbp:relatedTo |
gptkb:capsaicin
|
| gptkbp:toxicity |
extremely potent
|
| gptkbp:UNII |
1O5D6QF8ZW
|
| gptkbp:uses |
pain research
neuropathic pain treatment (experimental) |
| gptkbp:bfsParent |
gptkb:TRPV1_receptor
|
| gptkbp:bfsLayer |
6
|