TRP channel family

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy gptkb:temperature
ligands
voltage
mechanical stimuli
gptkbp:associatedWith kidney disease
neurological disorders
pain disorders
gptkbp:discoveredBy gptkb:Drosophila_melanogaster
gptkbp:discoveredIn 1989
gptkbp:foundIn animals
fungi
plants
gptkbp:fullName Transient Receptor Potential channel family
gptkbp:function cellular signaling
ion channel
sensory transduction
gptkbp:hasWikipediaPage https://en.wikipedia.org/wiki/Transient_receptor_potential_channel
https://www.w3.org/2000/01/rdf-schema#label TRP channel family
gptkbp:membraneLocation gptkb:plasma_membrane
endolysosomal membrane
gptkbp:MeSH_ID D054556
gptkbp:OMIM 603345
gptkbp:permeableTo magnesium ions
calcium ions
sodium ions
gptkbp:proteinFamily TRP genes
gptkbp:regulates gptkb:G-proteins
gptkb:calmodulin
protein kinases
phosphoinositides
intracellular calcium
gptkbp:relatedTo gptkb:DVD
taste
mechanosensation
chemosensation
pain sensation
thermosensation
osmolarity regulation
gptkbp:structure six transmembrane domains
pore-forming loop
gptkbp:subfamily gptkb:TRPA
TRPM
TRPC
TRPML
TRPP
TRPV
gptkbp:bfsParent gptkb:TRPV1_receptor
gptkbp:bfsLayer 6