|
gptkbp:instance_of
|
gptkb:chemical_compound
|
|
gptkbp:administered_by
|
gptkb:cream
|
|
gptkbp:bioavailability
|
low
|
|
gptkbp:business_model
|
approved
|
|
gptkbp:can_be_used_to
|
anti-inflammatory
|
|
gptkbp:casnumber
|
162632-80-0
|
|
gptkbp:chemical_formula
|
C18 H22 N2 O3 S
|
|
gptkbp:class
|
alkaloids
amide
|
|
gptkbp:clinical_trial
|
gptkb:various_countries
Phase II
pending
biotech firms
pain relief efficacy
|
|
gptkbp:clinical_trial_phase_i
|
completed
|
|
gptkbp:clinical_trial_phase_ii
|
ongoing
|
|
gptkbp:collaborations
|
universities and labs
|
|
gptkbp:composed_by
|
gptkb:chemical_compound
|
|
gptkbp:composed_of
|
stable under normal conditions
|
|
gptkbp:developed_by
|
gptkb:University_of_California
|
|
gptkbp:discovered_by
|
1990s
|
|
gptkbp:discovery_year
|
gptkb:1997
|
|
gptkbp:dissolved
|
soluble in ethanol
|
|
gptkbp:formulation
|
cream or gel
|
|
gptkbp:funding
|
grants
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
capsazepine
|
|
gptkbp:interacts_with
|
none reported
|
|
gptkbp:invention
|
pharmaceutical companies
patented
|
|
gptkbp:investigates
|
under review
cancer pain
|
|
gptkbp:investment
|
pain management market
|
|
gptkbp:market_position
|
not commercially available
|
|
gptkbp:marketed_as
|
experimental drug
|
|
gptkbp:mechanism_of_action
|
TRPV1 antagonist
|
|
gptkbp:notable_work
|
neuropathic pain studies
|
|
gptkbp:patient_population
|
adults
|
|
gptkbp:pharmacokinetics
|
limited absorption
TRPV1 inhibition
|
|
gptkbp:production_status
|
investigational
|
|
gptkbp:project
|
clinical trials
|
|
gptkbp:publication
|
gptkb:academic_journals
|
|
gptkbp:related_to
|
capsaicin
|
|
gptkbp:research
|
randomized controlled trials
|
|
gptkbp:research_areas
|
pain management
|
|
gptkbp:research_focus
|
chronic pain
neurological disorders
|
|
gptkbp:research_institutes
|
academic institutions
|
|
gptkbp:research_outcome_measure
|
pain scale
|
|
gptkbp:research_output
|
pain reduction
|
|
gptkbp:route_of_administration
|
topical
|
|
gptkbp:safety_features
|
under investigation
|
|
gptkbp:safety_measures
|
ongoing
|
|
gptkbp:side_effect
|
mild
skin irritation
|
|
gptkbp:structure
|
non-steroidal
|
|
gptkbp:targets
|
gptkb:TRPV1_receptor
diabetic neuropathy
|
|
gptkbp:therapeutic_index
|
gptkb:unknown
|
|
gptkbp:used_for
|
pain relief
|
|
gptkbp:weight
|
342.44 g/mol
|
|
gptkbp:bfsParent
|
gptkb:TRPV1
|
|
gptkbp:bfsLayer
|
6
|