sterol regulatory element-binding protein 1c
GPTKB entity
Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
transcription factor |
| gptkbp:activatedBy |
gptkb:insulin
|
| gptkbp:alternativeName |
gptkb:SREBP-1c
bHLHd1 SREBF1c |
| gptkbp:binds |
sterol regulatory element (SRE)
|
| gptkbp:cleavage |
gptkb:site-1_protease_(S1P)
gptkb:site-2_protease_(S2P) |
| gptkbp:domain |
basic helix-loop-helix leucine zipper domain
|
| gptkbp:encodedBy |
gptkb:SREBF1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| https://www.w3.org/2000/01/rdf-schema#label |
sterol regulatory element-binding protein 1c
|
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
17p11.2
|
| gptkbp:memberOf |
gptkb:SREBP_family
|
| gptkbp:OMIM |
184756
|
| gptkbp:precursorLocatedIn |
endoplasmic reticulum membrane
|
| gptkbp:regulates |
gptkb:SREBF1_gene
fatty acid synthesis downregulated by polyunsaturated fatty acids upregulated by insulin lipid biosynthesis triglyceride synthesis downregulated by cholesterol ACACA gene ACLY gene ELOVL6 gene FASN gene GPAM gene SCD1 gene |
| gptkbp:UniProtID |
P36956
|
| gptkbp:bfsParent |
gptkb:SREBP-1c
|
| gptkbp:bfsLayer |
7
|