Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
MBTPS1
membrane-bound transcription factor peptidase, site 1 |
| gptkbp:associatedWith |
Congenital disorder of glycosylation type II
|
| gptkbp:biologicalProcess |
serine protease activity
|
| gptkbp:cofactor |
calcium
|
| gptkbp:EC_number |
3.4.21.112
|
| gptkbp:family |
subtilisin-like proprotein convertase family
|
| gptkbp:function |
cleaves membrane-bound transcription factors
regulates cholesterol homeostasis regulates endoplasmic reticulum stress response |
| gptkbp:gene |
MBTPS1
|
| https://www.w3.org/2000/01/rdf-schema#label |
site-1 protease (S1P)
|
| gptkbp:locatedOnChromosome |
16q23.1
|
| gptkbp:location |
gptkb:Golgi_apparatus
|
| gptkbp:OMIM |
603355
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
type I membrane protein
|
| gptkbp:substrate |
gptkb:ATF6
SREBP |
| gptkbp:UniProtID |
Q14703
|
| gptkbp:bfsParent |
gptkb:SREBP-1c
|
| gptkbp:bfsLayer |
7
|