|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:activityDecreasedIn
|
gptkb:liver_disease
malnutrition
pregnancy
organophosphate poisoning
|
|
gptkbp:activityIncreasedIn
|
gptkb:nephrotic_syndrome
gptkb:diabetes_mellitus
obesity
|
|
gptkbp:alsoKnownAs
|
gptkb:pseudocholinesterase
gptkb:butyrylcholinesterase
|
|
gptkbp:deficiencyCauses
|
prolonged apnea after succinylcholine
|
|
gptkbp:EC_number
|
3.1.1.8
|
|
gptkbp:encodedBy
|
gptkb:BCHE_gene
|
|
gptkbp:foundIn
|
blood plasma
|
|
gptkbp:function
|
hydrolyzes choline-based esters
|
|
gptkbp:inhibitedBy
|
gptkb:organophosphates
carbamates
|
|
gptkbp:medicalUse
|
assessment of liver function
diagnosis of organophosphate poisoning
preoperative screening for succinylcholine sensitivity
|
|
gptkbp:notToBeConfusedWith
|
gptkb:acetylcholinesterase
|
|
gptkbp:OMIM
|
177400
|
|
gptkbp:range
|
3,700–10,400 U/L (varies by lab)
|
|
gptkbp:structure
|
gptkb:protein
|
|
gptkbp:substrate
|
gptkb:procaine
gptkb:succinylcholine
gptkb:butyrylcholine
|
|
gptkbp:synthesisType
|
liver
|
|
gptkbp:bfsParent
|
gptkb:BCHE
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
serum cholinesterase
|