|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alsoKnownAs
|
gptkb:butyrylcholinesterase
|
|
gptkbp:catalyzes
|
hydrolysis of choline-based esters
|
|
gptkbp:clinicalTrialPhase
|
dibucaine number
fluoride number
|
|
gptkbp:discoveredBy
|
gptkb:Ernst_August_Friedrich_Ruska
|
|
gptkbp:EC_number
|
3.1.1.8
|
|
gptkbp:encodedBy
|
gptkb:BCHE_gene
|
|
gptkbp:foundIn
|
blood plasma
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
pseudocholinesterase
|
|
gptkbp:inhibitedBy
|
gptkb:organophosphates
carbamates
|
|
gptkbp:location
|
gptkb:skin
gptkb:kidney
heart
lungs
gastrointestinal tract
central nervous system
liver
spleen
|
|
gptkbp:molecularWeight
|
~340 kDa
|
|
gptkbp:mutationAssociatedWith
|
atypical variants can cause drug sensitivity
|
|
gptkbp:notToBeConfusedWith
|
gptkb:acetylcholinesterase
|
|
gptkbp:OMIM
|
177400
|
|
gptkbp:significance
|
deficiency can cause prolonged apnea after succinylcholine
|
|
gptkbp:structure
|
tetramer
|
|
gptkbp:substrate
|
gptkb:procaine
gptkb:succinylcholine
cocaine
|
|
gptkbp:usedIn
|
diagnosis of liver function
|
|
gptkbp:bfsParent
|
gptkb:BCHE
gptkb:butyrylcholinesterase
gptkb:esterase
|
|
gptkbp:bfsLayer
|
7
|