|
gptkbp:instanceOf
|
gptkb:drug
neuromuscular blocking agent
|
|
gptkbp:administeredBy
|
general anesthesia
|
|
gptkbp:ATCCode
|
M03AB01
|
|
gptkbp:brand
|
Anectine
Quelicin
|
|
gptkbp:CASNumber
|
Succinate: 6101-15-1
|
|
gptkbp:category
|
muscle relaxant
choline ester
quaternary ammonium compound
|
|
gptkbp:chemicalFormula
|
C14H30N2O4
|
|
gptkbp:contraindication
|
malignant hyperthermia
personal or family history of pseudocholinesterase deficiency
|
|
gptkbp:discoveredBy
|
gptkb:Daniel_Bovet
|
|
gptkbp:discoveredIn
|
1949
|
|
gptkbp:duration
|
4 to 6 minutes
|
|
gptkbp:eliminationHalfLife
|
47 seconds
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
succinylcholine
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
depolarizing neuromuscular blocker
|
|
gptkbp:metabolism
|
gptkb:plasma_cholinesterase
|
|
gptkbp:onset
|
30 to 60 seconds
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:riskFactor
|
renal failure
muscular dystrophy
burn injury
crush injury
|
|
gptkbp:routeOfAdministration
|
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
malignant hyperthermia
bradycardia
hyperkalemia
muscle fasciculations
|
|
gptkbp:usedFor
|
facilitation of endotracheal intubation
muscle relaxation during surgery
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:plasma_cholinesterase
gptkb:pseudocholinesterase
gptkb:serum_cholinesterase
gptkb:peripheral_muscle_relaxants
|
|
gptkbp:bfsLayer
|
8
|