|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:acylcholine_acylhydrolase
gptkb:pseudocholinesterase
gptkb:serum_cholinesterase
|
|
gptkbp:associatedDrugResponse
|
mivacurium sensitivity
succinylcholine sensitivity
|
|
gptkbp:associatedWith
|
prolonged apnea after anesthesia
pseudocholinesterase deficiency
|
|
gptkbp:discoveredBy
|
gptkb:Ernest_Johnson_(enzyme,_1906)
|
|
gptkbp:encodes
|
gptkb:butyrylcholinesterase_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000114200
590
|
|
gptkbp:enzymeCommissionNumber
|
EC 3.1.1.8
|
|
gptkbp:expressedIn
|
gptkb:plasma
liver
|
|
gptkbp:fullName
|
gptkb:butyrylcholinesterase
|
|
gptkbp:function
|
hydrolyzes choline-based esters
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:983
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BCHE
|
|
gptkbp:locatedOnChromosome
|
gptkb:3q26.1-q26.2
|
|
gptkbp:OMIM
|
177400
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Bche
|
|
gptkbp:proteinFamily
|
serine hydrolase
|
|
gptkbp:significance
|
deficiency causes prolonged apnea after succinylcholine
mutations associated with pseudocholinesterase deficiency
|
|
gptkbp:UniProtID
|
gptkb:P06276
|
|
gptkbp:bfsParent
|
gptkb:Cholinesterase
|
|
gptkbp:bfsLayer
|
6
|