Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:receptor_tyrosine_kinase
gptkb:voltage-gated_potassium_channel gptkb:protein |
| gptkbp:binds |
serotonin
|
| gptkbp:discoveredIn |
1991
|
| gptkbp:encodedBy |
gptkb:HTR3A_gene
|
| gptkbp:enemyOf |
gptkb:ondansetron
gptkb:dolasetron gptkb:granisetron gptkb:palonosetron gptkb:tropisetron serotonin |
| gptkbp:family |
gptkb:Cys-loop_receptor_family
|
| gptkbp:foundIn |
central nervous system
peripheral nervous system |
| gptkbp:function |
mediates fast excitatory neurotransmission
|
| https://www.w3.org/2000/01/rdf-schema#label |
serotonin 5-HT3 receptor
|
| gptkbp:locatedOn |
neuronal membrane
|
| gptkbp:locatedOnChromosome |
chromosome 11 (HTR3A)
chromosome 11 (HTR3B) |
| gptkbp:permeableTo |
calcium ions
potassium ions sodium ions |
| gptkbp:relatedTo |
anxiety
irritable bowel syndrome nausea and vomiting |
| gptkbp:structure |
pentameric
|
| gptkbp:subunit |
gptkb:HTR3A
gptkb:HTR3B gptkb:HTR3C gptkb:HTR3D gptkb:HTR3E |
| gptkbp:target |
antiemetic drugs
|
| gptkbp:bfsParent |
gptkb:Cys-loop_receptor_family
|
| gptkbp:bfsLayer |
6
|