|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
ligand binding
|
|
gptkbp:alsoKnownAs
|
gptkb:Cys-loop_ligand-gated_ion_channel_family
|
|
gptkbp:contains
|
gptkb:GABA_A_receptor
gptkb:glutamate-gated_chloride_channel
gptkb:glycine_receptor
gptkb:serotonin_5-HT3_receptor
gptkb:zinc-activated_ion_channel
nicotinic acetylcholine receptor
|
|
gptkbp:Cys-loop
|
disulfide bond between two cysteines
loop of 13 amino acids
|
|
gptkbp:database
|
gptkb:InterPro:_IPR006202
gptkb:Pfam:_PF02932
|
|
gptkbp:evolvesFrom
|
eukaryotes
|
|
gptkbp:foundIn
|
animals
|
|
gptkbp:function
|
mediate fast synaptic transmission
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cys-loop receptor family
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:permeableTo
|
anion selective
cation selective
|
|
gptkbp:proteinFamily
|
gptkb:LGIC_family
|
|
gptkbp:relatedTo
|
target for drugs
target for insecticides
|
|
gptkbp:structure
|
pentameric
contains Cys-loop
|
|
gptkbp:superfamily
|
gptkb:pentameric_ligand-gated_ion_channels
|
|
gptkbp:bfsParent
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:bfsLayer
|
5
|