Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
serotonin 5-HT3 receptor antagonist |
| gptkbp:ATCCode |
A04AA06
|
| gptkbp:brand |
Navoban
|
| gptkbp:CASNumber |
89565-68-4
|
| gptkbp:contraindication |
hypersensitivity to tropisetron
|
| gptkbp:developer |
gptkb:Novartis
|
| gptkbp:eliminationHalfLife |
7-8 hours
|
| gptkbp:hasMolecularFormula |
C17H20N2O2
|
| https://www.w3.org/2000/01/rdf-schema#label |
tropisetron
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
blocks serotonin 5-HT3 receptors
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
B1 (Australia)
|
| gptkbp:proteinBinding |
71%
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
constipation
dizziness headache |
| gptkbp:status |
approved in several countries
|
| gptkbp:synonym |
Navoban
Tropisetron hydrochloride |
| gptkbp:usedFor |
chemotherapy-induced nausea and vomiting
postoperative nausea and vomiting prevention of nausea and vomiting |
| gptkbp:bfsParent |
gptkb:5-HT3_receptor
gptkb:serotonin_5-HT3_receptor |
| gptkbp:bfsLayer |
7
|