Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
5-HT3R-A
HTR3 serotonin receptor 3A |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:depression
anxiety disorders neurotransmission serotonergic synapse emesis |
| gptkbp:discoveredBy |
1991
|
| gptkbp:encodes |
5-HT3A receptor
|
| gptkbp:Entrez_Gene_ID |
3359
ENSG00000166736 |
| gptkbp:expressedIn |
central nervous system
peripheral nervous system |
| gptkbp:function |
ligand-gated ion channel activity
serotonin receptor activity |
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
HGNC:5293
|
| https://www.w3.org/2000/01/rdf-schema#label |
HTR3A gene
|
| gptkbp:locatedOnChromosome |
chromosome 11
|
| gptkbp:mutationAssociatedWith |
may affect response to antiemetic drugs
may influence psychiatric disorder susceptibility |
| gptkbp:OMIM |
182135
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Htr3a
|
| gptkbp:pathway |
neuroactive ligand-receptor interaction
serotonin receptor signaling pathway |
| gptkbp:product |
5-hydroxytryptamine receptor 3A
|
| gptkbp:transmembraneDomains |
4
|
| gptkbp:UniProtID |
P46098
|
| gptkbp:bfsParent |
gptkb:5-HT3_receptor
gptkb:serotonin_5-HT3_receptor |
| gptkbp:bfsLayer |
7
|