|
gptkbp:instanceOf
|
gptkb:drug
gptkb:serotonin_5-HT3_receptor_antagonist
|
|
gptkbp:approvalYear
|
1991
|
|
gptkbp:ATCCode
|
A04AA02
|
|
gptkbp:brand
|
gptkb:Kytril
gptkb:Sancuso
|
|
gptkbp:CASNumber
|
109889-09-0
|
|
gptkbp:discoveredBy
|
gptkb:Roche
|
|
gptkbp:drugClass
|
gptkb:antiemetic
|
|
gptkbp:eliminationHalfLife
|
9 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:hasMolecularFormula
|
C18H24N4O
|
|
gptkbp:interactsWith
|
other serotonergic drugs
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
blocks serotonin 5-HT3 receptors
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
312.41 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:routeOfAdministration
|
oral
transdermal
intravenous
|
|
gptkbp:sideEffect
|
constipation
dizziness
headache
QT prolongation
insomnia
|
|
gptkbp:usedFor
|
chemotherapy-induced nausea and vomiting
postoperative nausea and vomiting
radiotherapy-induced nausea and vomiting
prevention of nausea and vomiting
|
|
gptkbp:bfsParent
|
gptkb:serotonin_5-HT3_receptor
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
granisetron
|