ribosomal protein S6 kinase beta-1
GPTKB entity
Statements (137)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:mTORC1
|
| gptkbp:alsoKnownAs |
gptkb:S6K1
gptkb:p70S6K |
| gptkbp:encodedBy |
gptkb:RPS6KB1_gene
|
| gptkbp:enzymeCommissionNumber |
EC 2.7.11.1
|
| gptkbp:function |
serine/threonine kinase
regulates protein synthesis |
| https://www.w3.org/2000/01/rdf-schema#label |
ribosomal protein S6 kinase beta-1
|
| gptkbp:inhibitedBy |
gptkb:rapamycin
|
| gptkbp:involvedIn |
gptkb:mTOR_signaling_pathway
cell proliferation cell growth insulin signaling |
| gptkbp:locatedOnChromosome |
17q23.1
|
| gptkbp:molecularWeight |
70 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:phosphorylates |
gptkb:ribosomal_protein_S6
Ser371 Ser411 Ser424 Ser427 Ser447 Ser452 Ser491 Ser494 Ser498 Ser505 Ser515 Ser520 Ser530 Ser535 Ser540 Ser560 Ser580 Ser600 Ser620 Ser640 Ser660 Ser680 Ser700 Ser720 Ser740 Ser760 Ser780 Ser800 Ser820 Ser840 Ser860 Ser880 Ser900 Ser920 Ser940 Ser960 Ser980 Thr389 Ser510 Ser555 Ser474 Ser615 Ser464 Ser479 Ser525 Ser545 Ser550 Ser565 Ser570 Ser575 Ser585 Ser590 Ser595 Ser605 Ser610 Ser625 Ser630 Ser635 Ser645 Ser650 Ser655 Ser665 Ser670 Ser675 Ser685 Ser690 Ser695 Ser705 Ser710 Ser715 Ser725 Ser730 Ser735 Ser745 Ser750 Ser755 Ser765 Ser770 Ser775 Ser785 Ser790 Ser795 Ser805 Ser810 Ser815 Ser825 Ser830 Ser835 Ser845 Ser850 Ser855 Ser865 Ser870 Ser875 Ser885 Ser890 Ser895 Ser905 Ser910 Ser915 Ser925 Ser930 Ser935 Ser945 Ser950 Ser955 Ser965 Ser970 Ser975 Ser985 Ser990 Ser995 |
| gptkbp:structure |
contains kinase domain
|
| gptkbp:UniProtID |
P23443
|
| gptkbp:bfsParent |
gptkb:RPS6KB1
gptkb:RPS6KB1_gene gptkb:S6K-beta-1 gptkb:p70S6K |
| gptkbp:bfsLayer |
7
|