protein phosphatase 2A

GPTKB entity

Statements (54)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:PP2A
serine/threonine-protein phosphatase 2A
gptkbp:associatedWith gptkb:cancer
neurodegenerative diseases
gptkbp:biologicalProcess protein serine/threonine phosphatase activity
gptkbp:component cell signaling pathways
gptkbp:EC_number 3.1.3.16
gptkbp:foundIn eukaryotic cells
gptkbp:function dephosphorylation of serine/threonine residues
gptkbp:gene gptkb:PPP2R4
PPP2CA
PPP2CB
PPP2R1A
PPP2R1B
PPP2R2A
PPP2R2B
PPP2R2C
PPP2R2D
PPP2R3A
PPP2R3B
PPP2R3C
PPP2R3D
PPP2R5A
PPP2R5B
PPP2R5C
PPP2R5D
PPP2R5E
PPP2R6
https://www.w3.org/2000/01/rdf-schema#label protein phosphatase 2A
gptkbp:inhibitedBy gptkb:microcystin-LR
gptkb:okadaic_acid
gptkbp:locale gptkb:nucleus
gptkb:cytoplasm
gptkbp:regulates gptkb:MAPK_signaling_pathway
gptkb:Wnt_signaling_pathway
apoptosis
signal transduction
metabolism
cell division
cell growth
protein synthesis
DNA replication
cell cycle
protein degradation
cellular stress response
chromatin remodeling
gptkbp:subunit catalytic subunit (C)
regulatory subunit (B)
structural subunit (A)
gptkbp:bfsParent gptkb:tau_protein
gptkb:SET_protein
gptkb:Tau_protein
gptkbp:bfsLayer 7