Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
proteolytic cleavage
|
| gptkbp:alternativeSplicing |
multiple isoforms
|
| gptkbp:associatedWith |
gptkb:death-inducing_signaling_complex_(DISC)
|
| gptkbp:cleavedToForm |
active caspase-8
|
| gptkbp:domain |
gptkb:death_effector_domain
|
| gptkbp:encodedBy |
gptkb:CASP8_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
apoptosis regulation
|
| https://www.w3.org/2000/01/rdf-schema#label |
procaspase-8
|
| gptkbp:inhibitedBy |
gptkb:c-FLIP
|
| gptkbp:involvedIn |
extrinsic apoptotic signaling pathway
|
| gptkbp:locale |
gptkb:cytoplasm
|
| gptkbp:molecularWeight |
~55 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
immunodeficiency |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:predecessor |
gptkb:caspase-8
|
| gptkbp:UniProtID |
gptkb:Q14790
|
| gptkbp:bfsParent |
gptkb:caspase-8
|
| gptkbp:bfsLayer |
7
|