|
gptkbp:instanceOf
|
gptkb:Corticosteroid
|
|
gptkbp:approvedBy
|
1955
|
|
gptkbp:ATCCode
|
H02AB06
|
|
gptkbp:brand
|
Millipred
Orapred
Pediapred
Pred Forte
Pred Mild
Prelone
|
|
gptkbp:CASNumber
|
50-24-8
|
|
gptkbp:contraindication
|
systemic fungal infections
hypersensitivity to prednisolone
|
|
gptkbp:discoveredBy
|
gptkb:Arthur_Nobile
|
|
gptkbp:eliminationHalfLife
|
2-4 hours
|
|
gptkbp:foundIn
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:hasMolecularFormula
|
C21H28O5
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
glucocorticoid receptor agonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:relatedTo
|
gptkb:prednisone
gptkb:methylprednisolone
hydrocortisone
|
|
gptkbp:routeOfAdministration
|
oral
topical
intravenous
ophthalmic
|
|
gptkbp:sideEffect
|
gptkb:bone
gptkb:peptic_ulcer
gptkb:Cushing's_syndrome
immunosuppression
hypertension
mood changes
weight gain
insomnia
hyperglycemia
|
|
gptkbp:usedFor
|
gptkb:nephrotic_syndrome
gptkb:Crohn's_disease
asthma
ulcerative colitis
autoimmune diseases
rheumatoid arthritis
allergic reactions
adrenal insufficiency
organ transplant rejection prevention
inflammatory conditions
dermatologic diseases
multiple sclerosis exacerbations
ophthalmic diseases
|
|
gptkbp:bfsParent
|
gptkb:cortisone
gptkb:CYP3A4
gptkb:Glucocorticoid_receptor
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
prednisolone
|