|
gptkbp:instanceOf
|
gptkb:Corticosteroid
hormone
|
|
gptkbp:administeredBy
|
gptkb:drug
|
|
gptkbp:affiliatedWith
|
corticosteroids
|
|
gptkbp:aroma
|
odorless
|
|
gptkbp:ATCCode
|
H02AB10
|
|
gptkbp:bioavailability
|
variable
|
|
gptkbp:CASNumber
|
53-06-5
|
|
gptkbp:chemicalFormula
|
C21H28O5
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
systemic fungal infections
|
|
gptkbp:discoveredBy
|
gptkb:Edward_Calvin_Kendall
|
|
gptkbp:discoveredIn
|
1935
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:hasUNII
|
8P6F9QJ24D
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
cortisone
|
|
gptkbp:IUPACName
|
gptkb:(8S,9S,10R,13S,14S,17R)-17,21-dihydroxypregn-4-ene-3,11,20-trione
|
|
gptkbp:KEGGID
|
D00361
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
1949
|
|
gptkbp:meltingPoint
|
220°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
360.44 g/mol
|
|
gptkbp:predecessor
|
cortisol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:producedBy
|
adrenal cortex
|
|
gptkbp:proteinBinding
|
90%
|
|
gptkbp:PubChem_CID
|
222786
16962
DB01380
|
|
gptkbp:relatedTo
|
gptkb:prednisone
gptkb:prednisolone
hydrocortisone
|
|
gptkbp:routeOfAdministration
|
oral
topical
intramuscular injection
|
|
gptkbp:sideEffect
|
gptkb:bone
hypertension
weight gain
hyperglycemia
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:usedFor
|
gptkb:systemic_lupus_erythematosus
immunosuppression
rheumatoid arthritis
allergic reactions
anti-inflammatory therapy
adrenal insufficiency
|
|
gptkbp:bfsParent
|
gptkb:Tadeus_Reichstein
|
|
gptkbp:bfsLayer
|
6
|