phosphoinositide-3-kinase regulatory subunit 1

URI: https://gptkb.org/entity/phosphoinositide-3-kinase_regulatory_subunit_1
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:p85α
PI3-kinase p85-alpha
gptkbp:associatedWith gptkb:cancer
gptkb:agammaglobulinemia
SHORT syndrome
gptkbp:biologicalProcess protein binding
phosphatidylinositol 3-kinase regulatory activity
gptkbp:cellularComponent gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:Entrez_Gene_ID gptkb:ENSG00000145675
GC05P068015
gptkbp:expressedIn various tissues
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function regulatory subunit of phosphoinositide 3-kinase
gptkbp:gene gptkb:PIK3R1
gptkbp:HGNC_ID 8979
https://www.w3.org/2000/01/rdf-schema#label phosphoinositide-3-kinase regulatory subunit 1
gptkbp:interactsWith gptkb:IRS1
SH2 domain-containing proteins
phosphoinositide-3-kinase catalytic subunit alpha
gptkbp:involves gptkb:PI3K-Akt_signaling_pathway
gptkbp:length 724
gptkbp:locatedOnChromosome 5q13.1
gptkbp:mutationAssociatedWith impaired PI3K signaling
gptkbp:OMIM 171833
gptkbp:postTranslationalModification phosphorylation
gptkbp:RefSeq NM_181523
gptkbp:UniProtID gptkb:P27986
gptkbp:bfsParent gptkb:PIK3R1
gptkbp:bfsLayer 6