phosphoinositide-3-kinase regulatory subunit 1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:p85α PI3-kinase p85-alpha
gptkbp:associatedWith	gptkb:cancer gptkb:agammaglobulinemia SHORT syndrome
gptkbp:biologicalProcess	protein binding phosphatidylinositol 3-kinase regulatory activity
gptkbp:cellularComponent	gptkb:cytoplasm gptkb:plasma_membrane
gptkbp:Entrez_Gene_ID	gptkb:ENSG00000145675 GC05P068015
gptkbp:expressedIn	various tissues
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	regulatory subunit of phosphoinositide 3-kinase
gptkbp:gene	gptkb:PIK3R1
gptkbp:HGNC_ID	8979
gptkbp:interactsWith	gptkb:IRS1 SH2 domain-containing proteins phosphoinositide-3-kinase catalytic subunit alpha
gptkbp:involves	gptkb:PI3K-Akt_signaling_pathway
gptkbp:length	724
gptkbp:locatedOnChromosome	5q13.1
gptkbp:mutationAssociatedWith	impaired PI3K signaling
gptkbp:OMIM	171833
gptkbp:postTranslationalModification	phosphorylation
gptkbp:RefSeq	NM_181523
gptkbp:UniProtID	gptkb:P27986
gptkbp:bfsParent	gptkb:PIK3R1
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	phosphoinositide-3-kinase regulatory subunit 1