phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
GPTKB entity
Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:PI3-kinase_p110_alpha
gptkb:PIK3CA_protein |
| gptkbp:associatedWith |
gptkb:cancer
colorectal cancer |
| gptkbp:biologicalProcess |
kinase activity
|
| gptkbp:enzymeCommissionNumber |
2.7.1.153
|
| gptkbp:function |
catalyzes phosphorylation of phosphatidylinositol-4,5-bisphosphate
involved in PI3K/AKT signaling pathway |
| gptkbp:gene |
gptkb:PIK3CA
|
| https://www.w3.org/2000/01/rdf-schema#label |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
|
| gptkbp:interactsWith |
regulatory subunit p85
|
| gptkbp:locatedOnChromosome |
3q26.32
|
| gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:mutationAssociatedWith |
E545K
H1047R |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:subunit |
gptkb:phosphoinositide_3-kinase_(PI3K)_complex
|
| gptkbp:UniProtID |
gptkb:P42336
|
| gptkbp:bfsParent |
gptkb:PIK3CA
|
| gptkbp:bfsLayer |
5
|