|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:von_Hippel–Lindau_disease
clear cell renal cell carcinoma
|
|
gptkbp:discoveredBy
|
gptkb:Gregg_L._Semenza
gptkb:Peter_J._Ratcliffe
gptkb:William_Kaelin_Jr.
|
|
gptkbp:encodedBy
|
gptkb:VHL_gene
|
|
gptkbp:fullName
|
von Hippel–Lindau tumor suppressor protein
|
|
gptkbp:function
|
gptkb:tumor_suppressor
regulation of hypoxia-inducible factors (HIFs)
|
|
gptkbp:interactsWith
|
gptkb:HIF-1α
gptkb:RBX1
elongin B
elongin C
CUL2
|
|
gptkbp:length
|
213 amino acids
|
|
gptkbp:locatedOnChromosome
|
3p25-26
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
30 kDa
|
|
gptkbp:organism
|
gptkb:human
|
|
gptkbp:PDB
|
gptkb:1LM8
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:UniProtID
|
P40337
|
|
gptkbp:bfsParent
|
gptkb:von_Hippel-Lindau_protein
gptkb:VHL_syndrome
gptkb:von_Hippel-Lindau_protein_(VHL)
gptkb:VHL_protein
gptkb:Von_Hippel-Lindau_tumor_suppressor
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
pVHL
|