Von Hippel-Lindau tumor suppressor
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
gptkb:VHL_protein
gptkb:pVHL |
| gptkbp:associatedWith |
gptkb:Von_Hippel-Lindau_disease
|
| gptkbp:discoveredBy |
gptkb:Gregg_L._Semenza
gptkb:Peter_J._Ratcliffe gptkb:William_G._Kaelin_Jr. |
| gptkbp:encodedBy |
gptkb:VHL_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
tumor suppression
regulation of hypoxia-inducible factors |
| gptkbp:HGNC_ID |
HGNC:12687
|
| gptkbp:interactsWith |
gptkb:RBX1
elongin B elongin C CUL2 |
| gptkbp:locatedOnChromosome |
chromosome 3p25.3
|
| gptkbp:mutationAssociatedWith |
gptkb:hemangioblastoma
gptkb:pheochromocytoma clear cell renal cell carcinoma |
| gptkbp:OMIM |
608537
|
| gptkbp:regulates |
gptkb:HIF1A
HIF2A |
| gptkbp:UniProtID |
P40337
|
| gptkbp:bfsParent |
gptkb:VHL
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Von Hippel-Lindau tumor suppressor
|