von Hippel-Lindau protein

URI: https://gptkb.org/entity/von_Hippel-Lindau_protein

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:VHL_tumor_suppressor gptkb:pVHL
gptkbp:discoveredBy	gptkb:Gregg_L._Semenza gptkb:Peter_J._Ratcliffe gptkb:William_Kaelin_Jr.
gptkbp:encodedBy	gptkb:VHL_gene
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	gptkb:tumor_suppressor E3 ubiquitin ligase complex component
gptkbp:interactsWith	gptkb:hypoxia-inducible_factor_1-alpha
gptkbp:location	gptkb:nucleus gptkb:cytoplasm
gptkbp:mutationAssociatedWith	gptkb:hemangioblastoma gptkb:renal_cell_carcinoma gptkb:pheochromocytoma gptkb:von_Hippel-Lindau_disease
gptkbp:regulates	degradation of HIF1A
gptkbp:UniProtID	P40337
gptkbp:bfsParent	gptkb:HIF
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	von Hippel-Lindau protein