Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:VHL_tumor_suppressor
gptkb:pVHL |
| gptkbp:discoveredBy |
gptkb:Gregg_L._Semenza
gptkb:Peter_J._Ratcliffe gptkb:William_Kaelin_Jr. |
| gptkbp:encodedBy |
gptkb:VHL_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
tumor suppressor
E3 ubiquitin ligase complex component |
| https://www.w3.org/2000/01/rdf-schema#label |
von Hippel-Lindau protein
|
| gptkbp:interactsWith |
gptkb:hypoxia-inducible_factor_1-alpha
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:mutationAssociatedWith |
gptkb:hemangioblastoma
gptkb:pheochromocytoma gptkb:von_Hippel-Lindau_disease renal cell carcinoma |
| gptkbp:regulates |
degradation of HIF1A
|
| gptkbp:UniProtID |
P40337
|
| gptkbp:bfsParent |
gptkb:HIF
|
| gptkbp:bfsLayer |
7
|