|
gptkbp:instanceOf
|
class of drugs
|
|
gptkbp:broadcastOn
|
controlled substance
|
|
gptkbp:can_be_abused
|
yes
|
|
gptkbp:can_be_administered_by
|
oral route
intravenous route
intramuscular route
subcutaneous route
transdermal route
|
|
gptkbp:cause
|
addiction
tolerance
constipation
pruritus
hypotension
respiratory depression
sedation
euphoria
bradycardia
dependence
|
|
gptkbp:contraindication
|
acute asthma
paralytic ileus
severe respiratory depression
|
|
gptkbp:enemyOf
|
gptkb:naloxone
gptkb:naltrexone
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
opioid analgesics
|
|
gptkbp:includes
|
gptkb:methadone
gptkb:oxycodone
gptkb:codeine
gptkb:morphine
gptkb:hydromorphone
gptkb:tapentadol
gptkb:meperidine
gptkb:tramadol
gptkb:buprenorphine
hydrocodone
fentanyl
|
|
gptkbp:interactsWith
|
gptkb:monoamine_oxidase_inhibitors
antipsychotics
antidepressants
|
|
gptkbp:mechanismOfAction
|
bind to opioid receptors
|
|
gptkbp:overdose_can_cause
|
death
|
|
gptkbp:prescribes
|
palliative care
chronic pain
acute pain
cancer pain
postoperative pain
|
|
gptkbp:regulates
|
gptkb:Controlled_Substances_Act_(US)
|
|
gptkbp:risk_increased_by
|
gptkb:beer
gptkb:benzodiazepines
other CNS depressants
|
|
gptkbp:sideEffect
|
nausea
vomiting
itching
drowsiness
urinary retention
miosis
|
|
gptkbp:usedFor
|
pain management
|
|
gptkbp:bfsParent
|
gptkb:opioid
|
|
gptkbp:bfsLayer
|
6
|