Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:domain |
DNA-binding domain
oligomerization domain transactivation domain |
| gptkbp:Entrez_Gene_ID |
22059
|
| gptkbp:foundIn |
gptkb:Mus_musculus
|
| gptkbp:function |
tumor suppressor
transcription factor |
| gptkbp:gene |
gptkb:Trp53
|
| https://www.w3.org/2000/01/rdf-schema#label |
mouse p53 protein
|
| gptkbp:interactsWith |
gptkb:BAX
gptkb:p21 gptkb:MDM2 gptkb:CHK2 ATM |
| gptkbp:locatedOnChromosome |
chromosome 11
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
~53 kDa
|
| gptkbp:mutationAssociatedWith |
increased cancer risk
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination acetylation |
| gptkbp:regulates |
apoptosis
DNA repair angiogenesis cell cycle senescence |
| gptkbp:sequenceSimilarity |
human p53 protein
|
| gptkbp:structure |
tetramer
|
| gptkbp:UniProtID |
gptkb:P02340
|
| gptkbp:bfsParent |
gptkb:NP_031401
|
| gptkbp:bfsLayer |
7
|