|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Beta-globin
gptkb:Hemoglobin_beta_chain
|
|
gptkbp:associatedWith
|
Beta-thalassemia
Sickle cell anemia
|
|
gptkbp:biologicalProcess
|
oxygen transport
oxygen binding
|
|
gptkbp:cellularComponent
|
gptkb:hemoglobin_complex
|
|
gptkbp:disulfideBond
|
nan
|
|
gptkbp:domain
|
globin domain
|
|
gptkbp:EC_number
|
-
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000335295
|
|
gptkbp:expressedIn
|
erythrocytes
|
|
gptkbp:family
|
globin family
|
|
gptkbp:function
|
Involved in oxygen transport from the lung to the various peripheral tissues.
|
|
gptkbp:gene
|
gptkb:HBB
|
|
gptkbp:hasIsoform
|
1
|
|
gptkbp:HGNC_ID
|
4827
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P02340
|
|
gptkbp:InterPro
|
IPR002338
|
|
gptkbp:KEGGID
|
gptkb:hsa:3043
|
|
gptkbp:locatedOnChromosome
|
11
11p15.4
|
|
gptkbp:location
|
gptkb:Cytoplasm
|
|
gptkbp:molecularWeight
|
15867 Da
|
|
gptkbp:OMIM
|
141900
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Hbb-b1
rat Hbb
|
|
gptkbp:PDB
|
1A3N
2HBB
|
|
gptkbp:postTranslationalModification
|
gptkb:N-terminal_acetylation
|
|
gptkbp:protein_name
|
gptkb:Hemoglobin_subunit_beta
|
|
gptkbp:proteinFamily
|
PF00042
|
|
gptkbp:Reactome
|
gptkb:R-HSA-1237044
|
|
gptkbp:RefSeq
|
gptkb:NP_000509.1
|
|
gptkbp:sequence
|
147
MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH
|
|
gptkbp:sequenceStatus
|
Reviewed
|
|
gptkbp:signalPeptide
|
nan
|
|
gptkbp:subunit
|
Heterotetramer of two alpha and two beta chains
|
|
gptkbp:transmembraneDomains
|
nan
|
|
gptkbp:UniGene
|
Hs.654497
|
|
gptkbp:UniProt_entry_name
|
HBB_HUMAN
|
|
gptkbp:UniProtID
|
gptkb:P02340
|
|
gptkbp:bfsParent
|
gptkb:NP_031401
|
|
gptkbp:bfsLayer
|
7
|