|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:LXRα
gptkb:NR1H3
gptkb:LXR-alpha
|
|
gptkbp:encodedBy
|
Nr1h3 gene
|
|
gptkbp:expressedIn
|
liver
adipose tissue
macrophages
intestine
|
|
gptkbp:family
|
gptkb:nuclear_hormone_receptor_family
|
|
gptkbp:formsHeterodimerWith
|
gptkb:RXR_(Retinoid_X_receptor)
|
|
gptkbp:fullName
|
gptkb:Liver_X_receptor_alpha
|
|
gptkbp:function
|
transcription factor
nuclear receptor
|
|
gptkbp:gene
|
gptkb:Nr1h3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
mouse LXRα
|
|
gptkbp:ligand
|
oxysterols
|
|
gptkbp:locatedOnChromosome
|
chromosome 2
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:modulatedBy
|
ABCA1 expression
ApoE expression
CYP7A1 expression
FASN expression
SREBP-1c expression
|
|
gptkbp:molecularWeight
|
50 kDa
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
human LXRα
|
|
gptkbp:PDB
|
gptkb:1UHL
|
|
gptkbp:phosphorylates
|
Ser196
Ser198
|
|
gptkbp:regulates
|
lipid metabolism
cholesterol metabolism
inflammatory response
|
|
gptkbp:subfamily
|
NR1H
|
|
gptkbp:UniProtID
|
O55245
|
|
gptkbp:bfsParent
|
gptkb:LXRα
|
|
gptkbp:bfsLayer
|
7
|