Statements (41)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
nuclear receptor |
| gptkbp:activatedBy |
gptkb:9-cis-retinoic_acid
|
| gptkbp:discoveredIn |
1990
|
| gptkbp:domain |
DNA-binding domain
ligand-binding domain |
| gptkbp:encodedBy |
RXRA gene
RXRB gene RXRG gene |
| gptkbp:expressedIn |
many tissues
|
| gptkbp:familyMember |
gptkb:nuclear_hormone_receptor_family
|
| gptkbp:formsHeterodimerWith |
Constitutive androstane receptor (CAR)
Farnesoid X receptor (FXR) Liver X receptor (LXR) Peroxisome proliferator-activated receptor (PPAR) Pregnane X receptor (PXR) Retinoic acid receptor (RAR) Thyroid hormone receptor (TR) Vitamin D receptor (VDR) |
| gptkbp:function |
transcription regulation
gene expression modulation |
| gptkbp:hasIsoform |
gptkb:RXR_alpha
gptkb:RXR_beta gptkb:RXR_gamma |
| https://www.w3.org/2000/01/rdf-schema#label |
RXR (Retinoid X receptor)
|
| gptkbp:ligand |
gptkb:9-cis-retinoic_acid
|
| gptkbp:locatedIn |
cell nucleus
|
| gptkbp:regulates |
apoptosis
cell differentiation lipid metabolism glucose metabolism immune response |
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens gptkb:Rattus_norvegicus |
| gptkbp:symbol |
gptkb:RXR
|
| gptkbp:target |
gptkb:alitretinoin
gptkb:bexarotene pharmaceutical drugs |
| gptkbp:bfsParent |
gptkb:VDR
|
| gptkbp:bfsLayer |
7
|