RXR (Retinoid X receptor)

URI: https://gptkb.org/entity/RXR_(Retinoid_X_receptor)
GPTKB entity
Statements (41)
Predicate Object
gptkbp:instanceOf gptkb:nuclear_receptor
gptkb:protein
gptkbp:activatedBy gptkb:9-cis-retinoic_acid
gptkbp:discoveredIn 1990
gptkbp:domain DNA-binding domain
ligand-binding domain
gptkbp:encodedBy RXRA gene
RXRB gene
RXRG gene
gptkbp:expressedIn many tissues
gptkbp:familyMember gptkb:nuclear_hormone_receptor_family
gptkbp:formsHeterodimerWith Constitutive androstane receptor (CAR)
Farnesoid X receptor (FXR)
Liver X receptor (LXR)
Peroxisome proliferator-activated receptor (PPAR)
Pregnane X receptor (PXR)
Retinoic acid receptor (RAR)
Thyroid hormone receptor (TR)
Vitamin D receptor (VDR)
gptkbp:function transcription regulation
gene expression modulation
gptkbp:hasIsoform gptkb:RXR_alpha
gptkb:RXR_beta
gptkb:RXR_gamma
gptkbp:ligand gptkb:9-cis-retinoic_acid
gptkbp:locatedIn cell nucleus
gptkbp:regulates gptkb:immune_response
apoptosis
cell differentiation
lipid metabolism
glucose metabolism
gptkbp:species gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkb:Rattus_norvegicus
gptkbp:symbol gptkb:RXR
gptkbp:target gptkb:alitretinoin
gptkb:bexarotene
pharmaceutical drugs
gptkbp:bfsParent gptkb:VDR
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label RXR (Retinoid X receptor)