Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
transcription factor
nuclear receptor |
| gptkbp:activates_transcription_of |
gptkb:ABCA1
gptkb:CYP7A1 gptkb:SREBP-1c |
| gptkbp:alternativeName |
gptkb:LXRα
gptkb:NR1H3 |
| gptkbp:discoveredBy |
1995
|
| gptkbp:encodedBy |
gptkb:NR1H3_gene
|
| gptkbp:expressedIn |
liver
adipose tissue macrophages intestine |
| gptkbp:formsHeterodimerWith |
retinoid X receptor
|
| gptkbp:gene |
gptkb:NR1H3
|
| https://www.w3.org/2000/01/rdf-schema#label |
Liver X receptor alpha
|
| gptkbp:human_gene_ID |
7707
|
| gptkbp:ligand |
oxysterols
|
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
gptkb:11p11.2
|
| gptkbp:member |
gptkb:nuclear_receptor_subfamily_1_group_H_member_3
|
| gptkbp:orthologInMouse |
gptkb:Nr1h3
|
| gptkbp:regulates |
lipid metabolism
cholesterol metabolism inflammatory response genes involved in fatty acid synthesis genes involved in reverse cholesterol transport |
| gptkbp:targetOfDrug |
gptkb:GW3965
T0901317 |
| gptkbp:UniProtID |
Q13133
|
| gptkbp:bfsParent |
gptkb:LXRα
gptkb:NR1H3 |
| gptkbp:bfsLayer |
7
|