Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:LXRα
gptkb:LXR-alpha |
| gptkbp:biologicalProcess |
transcription regulation
lipid metabolic process nuclear receptor activity |
| gptkbp:cellularComponent |
gptkb:nucleus
|
| gptkbp:encodes |
Nuclear receptor subfamily 1, group H, member 3
|
| gptkbp:Entrez_Gene_ID |
MGI:109563
|
| gptkbp:expressedIn |
liver
adipose tissue macrophages intestine |
| gptkbp:function |
cholesterol homeostasis
regulation of lipid metabolism |
| gptkbp:gene |
gptkb:Nr1h3
|
| gptkbp:hasPhenotype |
altered cholesterol metabolism
impaired lipid homeostasis |
| https://www.w3.org/2000/01/rdf-schema#label |
Nr1h3
|
| gptkbp:ligand |
oxysterols
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_7_(mouse)
|
| gptkbp:organism |
gptkb:Mus_musculus
|
| gptkbp:orthologIn |
NR1H3 (human)
|
| gptkbp:pathway |
LXR/RXR activation pathway
|
| gptkbp:product |
gptkb:Liver_X_receptor_alpha
|
| gptkbp:regulates |
gptkb:ABCA1
gptkb:CYP7A1 gptkb:SREBP-1c |
| gptkbp:bfsParent |
gptkb:Liver_X_Receptor
gptkb:NR1H3 |
| gptkbp:bfsLayer |
7
|