Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:affiliatedWith |
gptkb:cytochrome_P450_superfamily
|
| gptkbp:expressedIn |
gptkb:hepatocytes
|
| gptkbp:function |
oxidation of small foreign organic molecules
|
| gptkbp:hasMember |
gptkb:CYP3A5
gptkb:CYP3A4 gptkb:CYP3A43 gptkb:CYP3A7 |
| gptkbp:inducedBy |
gptkb:rifampicin
gptkb:carbamazepine |
| gptkbp:inhibitedBy |
gptkb:milk
gptkb:ketoconazole |
| gptkbp:involvedIn |
drug metabolism
xenobiotic metabolism |
| gptkbp:locatedIn |
liver
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_7q21.1
|
| gptkbp:substrate |
gptkb:cyclosporine
gptkb:erythromycin gptkb:midazolam testosterone |
| gptkbp:bfsParent |
gptkb:lemborexant
gptkb:Belsomra gptkb:Zanubrutinib |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
liver (CYP3A)
|