|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:ALS
gptkb:IPOA
gptkb:SODC
gptkb:hSOD1
|
|
gptkbp:alternativeName
|
gptkb:ALS1
gptkb:Cu/Zn_superoxide_dismutase
|
|
gptkbp:associatedWith
|
gptkb:familial_amyotrophic_lateral_sclerosis
amyotrophic lateral sclerosis
|
|
gptkbp:biologicalProcess
|
antioxidant activity
response to oxidative stress
|
|
gptkbp:cellularComponent
|
gptkb:cytoplasm
mitochondrion
|
|
gptkbp:discoveredBy
|
gptkb:Irwin_Fridovich
|
|
gptkbp:discoveredIn
|
1969
|
|
gptkbp:encodes
|
gptkb:superoxide_dismutase_[Cu-Zn]
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000142168
6647
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:fullName
|
gptkb:superoxide_dismutase_1
|
|
gptkbp:function
|
catalyzes the dismutation of superoxide radicals
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOID
|
gptkb:GO:0004784
gptkb:GO:0005739
GO:0006979
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:11179
|
|
gptkbp:length
|
153
|
|
gptkbp:locatedOnChromosome
|
21
|
|
gptkbp:location
|
gptkb:21q22.11
|
|
gptkbp:molecularWeight
|
15.9 kDa
|
|
gptkbp:mutationAssociatedWith
|
linked to neurodegeneration
|
|
gptkbp:OMIM
|
147450
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Sod1
gptkb:yeast_SOD1
|
|
gptkbp:pathway
|
detoxification of reactive oxygen species
|
|
gptkbp:PDB
|
gptkb:1HL5
gptkb:1SPD
gptkb:2C9V
|
|
gptkbp:product
|
gptkb:SOD1_protein
|
|
gptkbp:RefSeq
|
gptkb:NM_000454
|
|
gptkbp:RefSeq_(protein)
|
NP_000445
|
|
gptkbp:regulates
|
induced by oxidative stress
|
|
gptkbp:UniProtID
|
gptkb:P00441
|
|
gptkbp:bfsParent
|
gptkb:SOD1-G93A_transgenic_mouse
gptkb:mouse_SOD1
gptkb:rat_SOD1
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
human SOD1
|