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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alternativeName
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gptkb:p120-RasGAP
Ras GTPase-activating protein 1
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gptkbp:associatedWith
|
gptkb:Parkes_Weber_syndrome
gptkb:capillary_malformation-arteriovenous_malformation_(CM-AVM)
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gptkbp:biologicalProcess
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signal transduction
angiogenesis
regulation of cell proliferation
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gptkbp:domain
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gptkb:PH_domain
C2 domain
SH2 domain
SH3 domain
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gptkbp:encodedBy
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gptkb:RASA1_gene
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gptkbp:Entrez_Gene_ID
|
5921
|
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gptkbp:function
|
GTPase-activating protein for Ras
negatively regulates Ras signaling pathway
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
human RASA1 protein
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gptkbp:interactsWith
|
gptkb:Ras_proteins
gptkb:Src_family_kinases
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gptkbp:length
|
1047 amino acids
|
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gptkbp:locatedOnChromosome
|
5q14.3
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gptkbp:location
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gptkb:cytoplasm
gptkb:plasma_membrane
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gptkbp:molecularWeight
|
120 kDa
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gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:Ras_signaling_pathway
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gptkbp:PDB
|
1WER
|
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gptkbp:postTranslationalModification
|
phosphorylation
|
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gptkbp:UniProtID
|
gptkb:P20936
ENSP00000361567
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gptkbp:bfsParent
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gptkb:GAP-1_protein
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gptkbp:bfsLayer
|
7
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