Statements (37)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
neurological disorder
|
| gptkbp:affects |
adults
more common in women |
| gptkbp:alsoKnownAs |
Moersch-Woltman syndrome
Stiff-man syndrome |
| gptkbp:associatedWith |
type 1 diabetes
autoimmune diseases vitiligo thyroiditis |
| gptkbp:cause |
autoimmune response
antibodies against glutamic acid decarboxylase (GAD) |
| gptkbp:characterizedBy |
muscle stiffness
muscle spasms increased sensitivity to stimuli |
| gptkbp:complication |
falls
disability |
| gptkbp:diagnosedBy |
gptkb:electromyography_(EMG)
clinical evaluation antibody testing |
| gptkbp:firstDescribed |
1956
Frederick Moersch Henry Woltman |
| https://www.w3.org/2000/01/rdf-schema#label |
Stiff-person syndrome
|
| gptkbp:notableCase |
gptkb:Céline_Dion
|
| gptkbp:prevalence |
rare
|
| gptkbp:symptom |
anxiety
rigidity difficulty walking painful muscle spasms |
| gptkbp:treatment |
gptkb:benzodiazepines
gptkb:baclofen immunotherapy plasmapheresis IVIG (intravenous immunoglobulin) |
| gptkbp:bfsParent |
gptkb:glutamate_decarboxylase
gptkb:amphiphysin |
| gptkbp:bfsLayer |
7
|