Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:anticoagulant |
| gptkbp:activatedBy |
gptkb:factor_VIIa
|
| gptkbp:alternativeName |
proconvertin
serum prothrombin conversion accelerator |
| gptkbp:cofactor |
gptkb:vitamin_A
|
| gptkbp:deficiencyCauses |
bleeding disorders
|
| gptkbp:discoveredBy |
Paul Owren
|
| gptkbp:discoveredIn |
1947
|
| gptkbp:EC_number |
3.4.21.21
|
| gptkbp:encodedBy |
F7 gene
|
| gptkbp:foundIn |
blood plasma
|
| gptkbp:function |
initiates blood coagulation
|
| https://www.w3.org/2000/01/rdf-schema#label |
factor VII
|
| gptkbp:involvedIn |
extrinsic pathway of coagulation
|
| gptkbp:locatedOnChromosome |
gptkb:13q34
|
| gptkbp:molecularWeight |
approximately 50 kDa
|
| gptkbp:synthesisType |
liver
|
| gptkbp:target |
recombinant factor VIIa therapy
|
| gptkbp:UniProtID |
P08709
|
| gptkbp:usedIn |
diagnosis of coagulation disorders
|
| gptkbp:bfsParent |
gptkb:coagulation_factors_II,_VII,_IX,_X
|
| gptkbp:bfsLayer |
5
|