Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
gptkb:factor_VIIa
gptkb:factor_IXa gptkb:factor_Xa |
| gptkbp:alternativeName |
gptkb:Stuart–Prower_factor
|
| gptkbp:cleavage |
prothrombin
|
| gptkbp:deficiencyCauses |
gptkb:bleeding_disorder
|
| gptkbp:discoveredBy |
Stuart and Prower
|
| gptkbp:EC_number |
3.4.21.6
|
| gptkbp:encodedBy |
gptkb:F10_gene
|
| gptkbp:function |
blood coagulation
|
| gptkbp:inhibitedBy |
gptkb:antithrombin
gptkb:tissue_factor_pathway_inhibitor |
| gptkbp:locatedOnChromosome |
gptkb:13q34
|
| gptkbp:location |
gptkb:plasma
|
| gptkbp:medicalUse |
diagnosis of coagulation disorders
|
| gptkbp:molecularWeight |
59 kDa
|
| gptkbp:OMIM |
227600
|
| gptkbp:produces |
gptkb:thrombin
|
| gptkbp:role |
common pathway of coagulation cascade
|
| gptkbp:species |
gptkb:human
mammals |
| gptkbp:target |
anticoagulant drugs
direct oral anticoagulants |
| gptkbp:UniProtID |
P00742
|
| gptkbp:bfsParent |
gptkb:F10_gene
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
coagulation factor X
|