|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:attention_deficit_hyperactivity_disorder
novelty seeking behavior
dopaminergic neurotransmission
|
|
gptkbp:biologicalProcess
|
G protein-coupled receptor signaling pathway
dopamine receptor activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
Van Tol et al.
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:encodes
|
D4 subtype of dopamine receptor
|
|
gptkbp:enemyOf
|
gptkb:clozapine
gptkb:haloperidol
dopamine
|
|
gptkbp:Entrez_Gene_ID
|
1815
|
|
gptkbp:expressedIn
|
brain
|
|
gptkbp:fullName
|
Dopamine receptor D4
|
|
gptkbp:function
|
modulation of neurotransmission
|
|
gptkbp:hasPolymorphism
|
variable number tandem repeat (VNTR) in exon 3
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3025
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DRD4
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
|
|
gptkbp:OMIM
|
126452
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:relatedTo
|
schizophrenia
substance abuse
psychiatric disorders
|
|
gptkbp:transmembraneDomains
|
7
|
|
gptkbp:UniProtID
|
gptkb:P21917
|
|
gptkbp:bfsParent
|
gptkb:dopamine_receptor_D4
|
|
gptkbp:bfsLayer
|
7
|