|
gptkbp:instanceOf
|
UniProt accession number
|
|
gptkbp:alternativeName
|
Dopamine D2 receptor
D2DR
|
|
gptkbp:amendedBy
|
Phosphorylation
Glycosylation
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
gptkb:Bipolar_disorder
Schizophrenia
|
|
gptkbp:biologicalProcess
|
G-protein coupled receptor activity
dopamine receptor activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:database
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:Entrez_Gene_ID
|
1813
ENSG00000149295
|
|
gptkbp:family
|
G-protein coupled receptor 1 family
|
|
gptkbp:function
|
G-protein coupled receptor for dopamine
|
|
gptkbp:gene
|
DRD2
|
|
gptkbp:GO
|
GO:0016021
GO:0004952
GO:0007186
|
|
gptkbp:hasIsoform
|
2
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3023
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P21917
|
|
gptkbp:ligand
|
gptkb:Dopamine
|
|
gptkbp:locatedOnChromosome
|
11
|
|
gptkbp:locusType
|
11q23.2
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
9606
|
|
gptkbp:orthologIn
|
Mouse Drd2
Rat Drd2
|
|
gptkbp:pathway
|
Dopaminergic synapse
|
|
gptkbp:PDB
|
gptkb:6LUQ
6CM4
7DFP
7JVR
|
|
gptkbp:protein_existence
|
Evidence at protein level
|
|
gptkbp:protein_name
|
gptkb:Dopamine_receptor_D2
|
|
gptkbp:refersTo
|
gptkb:Dopamine_receptor_D2
|
|
gptkbp:RefSeq
|
NP_000786.1
|
|
gptkbp:reviewedBy
|
Yes
|
|
gptkbp:sequence
|
443
|
|
gptkbp:sequenceStatus
|
Complete
|
|
gptkbp:subfamily
|
Dopamine receptor subfamily
|
|
gptkbp:targetOfDrug
|
Parkinson's disease drugs
Antipsychotic drugs
|
|
gptkbp:tissue_specificity
|
gptkb:Brain
|
|
gptkbp:transmembraneDomains
|
Yes
|
|
gptkbp:type
|
Adenylyl cyclase inhibition
|
|
gptkbp:bfsParent
|
gptkb:dopamine_receptor_D4
|
|
gptkbp:bfsLayer
|
7
|