cytochrome P450, family 2, subfamily D, polypeptide 6
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:CYP2D6
gptkb:debrisoquine_4-hydroxylase |
| gptkbp:associatedWith |
poor metabolizer phenotype
ultrarapid metabolizer phenotype extensive metabolizer phenotype intermediate metabolizer phenotype |
| gptkbp:EC_number |
1.14.14.1
|
| gptkbp:encodedBy |
gptkb:CYP2D6_gene
|
| gptkbp:enzyme |
monooxygenase
|
| gptkbp:expressedIn |
brain
liver |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:gene |
gptkb:CYP2D6
|
| gptkbp:hasPolymorphism |
highly polymorphic
|
| https://www.w3.org/2000/01/rdf-schema#label |
cytochrome P450, family 2, subfamily D, polypeptide 6
|
| gptkbp:involves |
drug metabolism
xenobiotic metabolism |
| gptkbp:locatedOnChromosome |
gptkb:22q13.2
chromosome 22 |
| gptkbp:metabolism |
gptkb:codeine
gptkb:tamoxifen beta blockers antipsychotics antidepressants |
| gptkbp:OMIM |
124030
|
| gptkbp:significance |
pharmacogenomics
|
| gptkbp:UniProtID |
P10635
|
| gptkbp:bfsParent |
gptkb:cytochrome_P450_2D6
|
| gptkbp:bfsLayer |
6
|