Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
gptkb:thrombin
gptkb:factor_XIIa |
| gptkbp:alternativeName |
activated factor XI
FXIa |
| gptkbp:biologicalProcess |
serine-type endopeptidase activity
|
| gptkbp:CASNumber |
9001-28-9
|
| gptkbp:catalyzes |
activation of factor IX to IXa
|
| gptkbp:EC_number |
3.4.21.27
|
| gptkbp:encodedBy |
gptkb:F11_gene
|
| gptkbp:foundIn |
gptkb:plasma
|
| gptkbp:hasRole |
blood coagulation
|
| https://www.w3.org/2000/01/rdf-schema#label |
coagulation factor XIa
|
| gptkbp:inhibitedBy |
gptkb:alpha-1_antitrypsin
gptkb:C1-inhibitor gptkb:antithrombin_III gptkb:protein_Z-dependent_protease_inhibitor |
| gptkbp:involvedIn |
intrinsic pathway of coagulation
|
| gptkbp:isActivatedFrom |
gptkb:factor_XI
|
| gptkbp:partOf |
coagulation cascade
|
| gptkbp:producedBy |
liver
|
| gptkbp:structure |
homodimer
|
| gptkbp:target |
anticoagulant drugs
factor XIa inhibitors |
| gptkbp:UniProtID |
gptkb:P03951
|
| gptkbp:bfsParent |
gptkb:C1-inhibitor
|
| gptkbp:bfsLayer |
8
|