|
gptkbp:instanceOf
|
gptkb:protein
gptkb:serine_protease
|
|
gptkbp:administeredBy
|
intravenous injection
|
|
gptkbp:alternativeName
|
gptkb:C1_esterase_inhibitor
gptkb:C1INH
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:deficiencyCauses
|
gptkb:hereditary_hemorrhagic_telangiectasia
|
|
gptkbp:encodedBy
|
gptkb:SERPING1_gene
|
|
gptkbp:foundIn
|
human plasma
|
|
gptkbp:glycosylation
|
heavily glycosylated
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
C1-inhibitor
|
|
gptkbp:inhibitedBy
|
gptkb:MASP-1
gptkb:MASP-2
gptkb:C1r
gptkb:C1s
gptkb:coagulation_factor_XIa
gptkb:kallikrein
gptkb:factor_XIIa
plasmin
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_11q12-q13.1
|
|
gptkbp:medicalUse
|
treatment of hereditary angioedema
|
|
gptkbp:molecularWeight
|
~105 kDa
|
|
gptkbp:OMIM
|
606860
|
|
gptkbp:producedBy
|
liver
|
|
gptkbp:regulates
|
gptkb:coagulation_system
gptkb:fibrinolytic_system
complement system
contact system
|
|
gptkbp:structure
|
gptkb:protein
|
|
gptkbp:UniProtID
|
P05155
|
|
gptkbp:usedAs
|
therapeutic agent
|
|
gptkbp:bfsParent
|
gptkb:FXI
gptkb:serpins
gptkb:factor_XIa
|
|
gptkbp:bfsLayer
|
7
|