Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
blood coagulation factor |
gptkbp:activatedBy |
gptkb:factor_IX
gptkb:thrombin gptkb:factor_XIIa |
gptkbp:alternativeName |
gptkb:PTA
gptkb:plasma_thromboplastin_antecedent |
gptkbp:deficiencyCauses |
gptkb:hemophilia_C
|
gptkbp:discoveredBy |
Rosenthal et al.
|
gptkbp:EC_number |
3.4.21.27
|
gptkbp:encodedBy |
gptkb:F11_gene
|
gptkbp:foundIn |
human blood plasma
|
gptkbp:function |
initiates intrinsic pathway of blood coagulation
|
https://www.w3.org/2000/01/rdf-schema#label |
factor XI
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_4q35
|
gptkbp:molecularWeight |
approximately 160 kDa
|
gptkbp:OMIM |
264900
|
gptkbp:presentIn |
mammals
|
gptkbp:structure |
homodimer
|
gptkbp:synthesisType |
liver
|
gptkbp:UniProtID |
gptkb:P03951
|
gptkbp:bfsParent |
gptkb:thrombin_(F2)
gptkb:F11_gene gptkb:factor_XIa |
gptkbp:bfsLayer |
7
|