chronic lymphoid leukemia

URI: https://gptkb.org/entity/chronic_lymphoid_leukemia
GPTKB entity
Statements (52)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkb:hematologic_cancer
gptkbp:abbreviation gptkb:CLL
gptkbp:affects blood
bone marrow
lymphocytes
gptkbp:alsoKnownAs chronic lymphocytic leukemia
gptkbp:associatedWith gptkb:trisomy_12
chromosome 11q deletion
chromosome 13q deletion
chromosome 17p deletion
gptkbp:complication gptkb:autoimmune_hemolytic_anemia
infections
Richter transformation
gptkbp:diagnosedBy gptkb:blood_test
bone marrow biopsy
gptkbp:firstDescribed gptkb:19th_century
gptkbp:hasCellMarker gptkb:CD20
gptkb:CD19
gptkb:CD23
CD5
gptkbp:hasSurvivalRate 5-year survival over 80% (early stage)
lower in advanced stage
gptkbp:ICD-10_code C91.1
gptkbp:incidence higher in Western countries
rare in Asia
gptkbp:medianAge about 70 years
gptkbp:offersCourse indolent
can become aggressive
gptkbp:originatedIn gptkb:B_cell
gptkbp:prevalence most common leukemia in adults
gptkbp:prognosis variable
gptkbp:riskFactor age
family history
male sex
gptkbp:stageName Binet system
Rai system
gptkbp:subclassOf gptkb:leukemia
gptkbp:symptom fever
fatigue
weight loss
night sweats
enlarged lymph nodes
gptkbp:transformsInto gptkb:Richter's_syndrome
gptkbp:treatment gptkb:immunotherapy
gptkb:targeted_therapy
chemotherapy
stem cell transplant
gptkbp:bfsParent gptkb:hairy_cell_leukemia
gptkb:CLL
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label chronic lymphoid leukemia