Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
hematologic cancer |
| gptkbp:abbreviation |
gptkb:CLL
|
| gptkbp:affects |
blood
bone marrow lymphocytes |
| gptkbp:alsoKnownAs |
chronic lymphocytic leukemia
|
| gptkbp:associatedWith |
gptkb:trisomy_12
chromosome 11q deletion chromosome 13q deletion chromosome 17p deletion |
| gptkbp:complication |
gptkb:autoimmune_hemolytic_anemia
infections Richter transformation |
| gptkbp:diagnosedBy |
blood test
bone marrow biopsy |
| gptkbp:firstDescribed |
19th century
|
| gptkbp:hasCellMarker |
gptkb:CD20
gptkb:CD19 gptkb:CD23 CD5 |
| gptkbp:hasSurvivalRate |
5-year survival over 80% (early stage)
lower in advanced stage |
| https://www.w3.org/2000/01/rdf-schema#label |
chronic lymphoid leukemia
|
| gptkbp:ICD-10_code |
C91.1
|
| gptkbp:incidence |
higher in Western countries
rare in Asia |
| gptkbp:medianAge |
about 70 years
|
| gptkbp:offersCourse |
indolent
can become aggressive |
| gptkbp:originatedIn |
gptkb:B_cell
|
| gptkbp:prevalence |
most common leukemia in adults
|
| gptkbp:prognosis |
variable
|
| gptkbp:riskFactor |
age
family history male sex |
| gptkbp:stageName |
Binet system
Rai system |
| gptkbp:subclassOf |
leukemia
|
| gptkbp:symptom |
fever
fatigue weight loss night sweats enlarged lymph nodes |
| gptkbp:transformsInto |
gptkb:Richter's_syndrome
|
| gptkbp:treatment |
chemotherapy
immunotherapy targeted therapy stem cell transplant |
| gptkbp:bfsParent |
gptkb:hairy_cell_leukemia
gptkb:CLL |
| gptkbp:bfsLayer |
7
|