Richter's syndrome

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:affects humans
gptkbp:alsoKnownAs Richter transformation
gptkbp:characterizedBy transformation of CLL into aggressive lymphoma
gptkbp:diagnosedBy biopsy
imaging studies
clinical features
gptkbp:eponymOf Maurice Richter
gptkbp:firstDescribed 1928
Maurice Richter
https://www.w3.org/2000/01/rdf-schema#label Richter's syndrome
gptkbp:ICD-10_code C91.1
gptkbp:isA complication of chronic lymphocytic leukemia
hematological malignancy
gptkbp:lessCommonTransformation Hodgkin lymphoma
gptkbp:MeSH_ID D018223
gptkbp:mostCommonTransformation diffuse large B-cell lymphoma
gptkbp:OMIM 605027
gptkbp:prognosis poor
gptkbp:riskFactor chronic lymphocytic leukemia
gptkbp:symptom fever
weight loss
night sweats
rapidly enlarging lymph nodes
gptkbp:treatment chemotherapy
immunotherapy
stem cell transplantation
gptkbp:bfsParent gptkb:CLL
gptkbp:bfsLayer 7